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Tocris Bioscience™ HC 067047
Potent and selective TRPV4 antagonist
Brand: Tocris Bioscience™ 4100/10
Additional Details : Weight : 0.00970kg
Description
HC 067047 is a potent and selective TRPV4 antagonist. Reversibly inhibits currents through mouse, human and rat TRPV4 orthologs (IC50 values are 17, 48 and 133 nM respectively). Also inhibits the endogenous TRPV4-mediated response to 4α-PDH (IC50 = 22 nM). Selective for TRPV4 over TRPV1, TRPV2, TRPV3 and TRPM8 channels.Specifications
2-Methyl-1-[3-(4-morpholinyl)propyl]-5-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide | |
10 mg | |
C26H28F3N3O2 |
883031-03-6 | |
TRPV Antagonists | |
0.99 |