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Invitrogen™ Human CD200 His-tag Recombinant Protein
Recombinant Protein
Brand: Invitrogen™ RP87981
Additional Details : Weight : 0.01000kg
Description
CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains, and belongs to the immunoglobulin superfamily. CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation. Distant, but recognizable, homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies of the related genes in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms of CD200 have been found. Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.Specifications
P41217 | |
Lyophilized | |
4345 | |
Cd200 | |
1 mg | |
RUO | |
antigen identified by monoclonal antibody MRC OX-2; CD200; Cd200 antigen; Cd200 molecule; cell surface protein (thymocyte antigen identified by monoclonal antibody MRC-O x 2); Cspmo2; hypothetical protein LOC534910; MO x 1; MO x 2; MRC; MRC OX-2 antigen; MRCO x 2; My033; O x 2; OX-2; OX-2 membrane glycoprotein | |
Protein | |
Unconjugated | |
Human CD200, amino acids Met1-Gly232 (Accession # NP_005935.4) with a C-terminal His-tag | |
HEK293 cells |
ELISA | |
PBS with 0.01% mannitol, 0.01% Tween 80, 5-8% trehalose and no preservative; pH 7.4 | |
40-45 kDa | |
SDS-PAGE | |
-20°C, Avoid Freeze/Thaw Cycles | |
<1.0 EU/ μg | |
Cd200 | |
Human | |
Recombinant | |
Immobilized CD200 Protein, Human, Recombinant (His Tag) (at 2 μg/mL (100 μL/well) can bind CD200R Protein, Human, Recombinant (His and hFc Tag), the EC50 is 5-28 ng/mL) | |
>98% as determined by SDS-PAGE. |