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Invitrogen™ Human CD200 His-tag Recombinant Protein

Recombinant Protein

£285.00 - £1854.00

Specifications

Accession Number P41217
For Use With (Application) ELISA
Format Lyophilized
Formulation PBS with 0.01% mannitol, 0.01% Tween 80, 5-8% trehalose and no preservative; pH 7.4
Gene ID (Entrez) 4345
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Product Code Brand Quantity Price Quantity & Availability  
17926511
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Invitrogen™
RP87981
1 mg
£1854.00
1mg
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Estimated Shipment: 20-08-2024
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17965831
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Invitrogen™
RP87980
100 μg
£285.00
100µg
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Estimated Shipment: 20-08-2024
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Description

Description

CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains, and belongs to the immunoglobulin superfamily. CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation. Distant, but recognizable, homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies of the related genes in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms of CD200 have been found. Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.
Specifications

Specifications

P41217
Lyophilized
4345
Cd200
-20°C, Avoid Freeze/Thaw Cycles
<1.0 EU/ μg
Cd200
Human
Recombinant
Immobilized CD200 Protein, Human, Recombinant (His Tag) (at 2 μg/mL (100 μL/well) can bind CD200R Protein, Human, Recombinant (His and hFc Tag), the EC50 is 5-28 ng/mL)
>98% as determined by SDS-PAGE.
ELISA
PBS with 0.01% mannitol, 0.01% Tween 80, 5-8% trehalose and no preservative; pH 7.4
40-45 kDa
SDS-PAGE
RUO
antigen identified by monoclonal antibody MRC OX-2; CD200; Cd200 antigen; Cd200 molecule; cell surface protein (thymocyte antigen identified by monoclonal antibody MRC-O x 2); Cspmo2; hypothetical protein LOC534910; MO x 1; MO x 2; MRC; MRC OX-2 antigen; MRCO x 2; My033; O x 2; OX-2; OX-2 membrane glycoprotein
Protein
Unconjugated
Human CD200, amino acids Met1-Gly232 (Accession # NP_005935.4) with a C-terminal His-tag
HEK293 cells
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