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Gibco™ Human Epiregulin Recombinant Protein, PeproTech®
E. coli Recombinant Protein
Brand: Gibco™ 100-04-500UG
This item is not returnable.
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Description
Epiregulin is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes, as well as in certain carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. It also inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence.Specifications
O14944 | |
protein with no preservative | |
5.6 | |
500 μg | |
-20°C | |
<1 EU/μg | |
Ereg | |
Unconjugated | |
MVAQVSITKC SSDMNGYCLH GQCIYLVDMS QNYCRCEVGY TGVRCEHFFL | |
≥ 98% by SDS-PAGE gel and HPLC analyses. |
Functional Assay | |
2069 | |
Human Epiregulin | |
E. coli | |
RUO | |
Ep; Epiregulin; EPR; ER; EREG; Proepiregulin | |
Human | |
Recombinant | |
Lyophilized |