Gibco™ Human Epiregulin Recombinant Protein, PeproTech®

E. coli Recombinant Protein

Product Code	Brand	Quantity
17850473	Gibco™ 100-04-100UG	100 μg
17830093	Gibco™ 100-04-1MG	1 mg
17880543	Gibco™ 100-04-250UG	250 μg
17841423	Gibco™ 100-04-25UG	25 μg
17810763	Gibco™ 100-04-500UG	500 μg
17810263	Gibco™ 100-04-5UG	5 μg

Description

Epiregulin is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes, as well as in certain carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. It also inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence.

Specifications

• Accession Number: O14944
• Formulation: protein with no preservative
• Molecular Weight (g/mol): 5.6
• Source: E. coli
• Regulatory Status: RUO
• Gene Alias: Ep; Epiregulin; EPR; ER; EREG; Proepiregulin
• Specific Reactivity: Human
• Recombinant: Recombinant
• Form: Lyophilized

• For Use With (Application): Functional Assay
• Gene ID (Entrez): 2069
• Name: Human Epiregulin
• Storage Requirements: -20°C
• Endotoxin Concentration: <1 EU/μg
• Gene Symbol: Ereg
• Conjugate: Unconjugated
• Sequence: MVAQVSITKC SSDMNGYCLH GQCIYLVDMS QNYCRCEVGY TGVRCEHFFL
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.