Gibco™ Human IL-34 Recombinant Protein, PeproTech®

HEK293 cells Recombinant Protein

Product Code	Brand	Quantity
17821883	Gibco™ 200-34-100UG	100 μg
17850433	Gibco™ 200-34-10UG	10 μg
30089736	Gibco™ 200-34-01M	2 x 500 μg
17810063	Gibco™ 200-34-1MG	2 x 500 μg
17870433	Gibco™ 200-34-250UG	250 μg
17821813	Gibco™ 200-34-2UG	2 μg
17850443	Gibco™ 200-34-500UG	500 μg
17871873	Gibco™ 200-34-50UG	50 μg

Description

IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.

Specifications

• Accession Number: Q6ZMJ4
• Gene ID (Entrez): 146433
• Name: Human IL-34
• Storage Requirements: -20°C
• Endotoxin Concentration: <1 EU/μg
• Gene Symbol: Il34
• Conjugate: Unconjugated
• Sequence: NEPLEMWPLT QNEECTVTGF LRDKLQYRSR LQYMKHYFPI NYKISVPYEG VFRIANVTRL QRAQVSEREL RYLWVLVSLS ATESVQDVLL EGHPSWKYLQ EVETLLLNVQ QGLTDVEVSP KVESVLSLLN APGPNLKLVR PKALLDNCFR VMELLYCSCC KQSSVLNWQD CEVPSPQSCS PEPSLQYAAT QLYPPPPWSP SSPPHSTGSV RPVRAQGEGL LPHHHHHHHH
• Purity or Quality Grade: ≥ 95% by SDS-PAGE gel and HPLC analyses.

• For Use With (Application): Functional Assay
• Molecular Weight (g/mol): 52.5
• Source: HEK293 cells
• Regulatory Status: RUO
• Gene Alias: 2010004A03Rik; AI593503; C16orf77; IL34; IL-34; ILN; Interleukin; interleukin 34; Interleukin34; interleukin-34
• Specific Reactivity: Human
• Recombinant: Recombinant
• Form: Lyophilized