Gibco™ Human MD-2/LY96 Recombinant Protein, PeproTech®

HEK293 cells Recombinant Protein

Product Code	Brand	Quantity
17810033	Gibco™ 160-07-100UG	100 μg
17831523	Gibco™ 160-07-10UG	10 μg
17800033	Gibco™ 160-07-1MG	1 mg
17860283	Gibco™ 160-07-250UG	250 μg
17810713	Gibco™ 160-07-500UG	500 μg
17831753	Gibco™ 160-07-50UG	50 μg

Description

Toll-like receptors (TLRs) are evolutionarily conserved patternrecognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD -1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.

Specifications

• Accession Number: Q9Y6Y9
• Formulation: protein with no preservative
• Molecular Weight (g/mol): 17.2
• Source: HEK293 cells
• Regulatory Status: RUO
• Gene Alias: Esop1; ESOP-1; LPS co-receptor MD-2; LY96; ly-96; Lymphocyte antigen 96; MD2; MD-2; myeloid differentiation factor-2; myeloid differentiation protein-2; protein MD-2
• Specific Reactivity: Human
• Recombinant: Recombinant
• Form: Lyophilized

• For Use With (Application): ELISA, Functional Assay
• Gene ID (Entrez): 23643
• Name: Human MD-2/LY96
• Storage Requirements: -20°C
• Endotoxin Concentration: <1 EU/μg
• Gene Symbol: LY96
• Conjugate: Unconjugated
• Sequence: QKQYWVCNSS DASISYTYCD KMQYPISINV NPCIELKGSK GLLHIFYIPR RDLKQLYFNL YITVNTMNLP KRKEVICRGS DDDYSFCRAL KGETVNTTIS FSFKGIKFSK GKYKCVVEAI SGSPEEMLFC LEFVILHQPN SNHHHHHH
• Purity or Quality Grade: ≥ 90% by SDS-PAGE gel and HPLC analyses.