Thermo Scientific™ Hypersil™ Chiral HPLC Columns

Product Code	Brand	Length (Metric)	Diameter (Metric)	Particle Size	Stationary Phase
16343117	Thermo Scientific™ 42003-054630	50 mm	4.6 mm	3 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
16333157	Thermo Scientific™ Chiral KIT 10UM 100	100 mm	4.6 mm	10 μm
16353117	Thermo Scientific™ 42003-104630	100 mm	4.6 mm	3 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
16343157	Thermo Scientific™ Chiral KIT 10UM 150	150 mm	4.6 mm	10 μm
16363117	Thermo Scientific™ 42003-154630	150 mm	4.6 mm	3 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
16353157	Thermo Scientific™ Chiral KIT 10UM 250	250 mm	4.6 mm	10 μm
16373117	Thermo Scientific™ 42003-254630	250 mm	4.6 mm	3 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
16363157	Thermo Scientific™ Chiral KIT 3UM 100	100 mm	4.6 mm	3 μm
16383117	Thermo Scientific™ 42005-104630	100 mm	4.6 mm	5 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
16373157	Thermo Scientific™ Chiral KIT 3UM 150	150 mm	4.6 mm	3 μm
16393117	Thermo Scientific™ 42005-154630	150 mm	4.6 mm	5 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
16383157	Thermo Scientific™ Chiral KIT 3UM 250	250 mm	4.6 mm	3 μm
16303127	Thermo Scientific™ 42005-254630	250 mm	4.6 mm	5 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
16393157	Thermo Scientific™ Chiral KIT 5UM 100	100 mm	4.6 mm	5 μm
16313127	Thermo Scientific™ 42005-259070A	250 mm	10 mm	5 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
16303167	Thermo Scientific™ Chiral KIT 5UM 150	150 mm	4.6 mm	5 μm
16323127	Thermo Scientific™ 42005-259270A	250 mm	20 mm	5 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
16313167	Thermo Scientific™ Chiral KIT 5UM 250	250 mm	4.6 mm	5 μm
16333127	Thermo Scientific™ 42010-104630	100 mm	4.6 mm	10 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
16343127	Thermo Scientific™ 42010-154630	150 mm	4.6 mm	10 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
16353127	Thermo Scientific™ 42010-254630	250 mm	4.6 mm	10 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
16363127	Thermo Scientific™ 42010-259070A	250 mm	10 mm	10 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
16373127	Thermo Scientific™ 42010-259270A	250 mm	20 mm	10 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
16383127	Thermo Scientific™ 42103-054630	50 mm	4.6 mm	3 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
16393127	Thermo Scientific™ 42103-104630	100 mm	4.6 mm	3 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
16303137	Thermo Scientific™ 42103-154630	150 mm	4.6 mm	3 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
16313137	Thermo Scientific™ 42103-254630	250 mm	4.6 mm	3 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
16323137	Thermo Scientific™ 42105-104630	100 mm	4.6 mm	5 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
16333137	Thermo Scientific™ 42105-154630	150 mm	4.6 mm	5 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
16343137	Thermo Scientific™ 42105-254630	250 mm	4.6 mm	5 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
16353137	Thermo Scientific™ 42105-259070A	250 mm	10 mm	5 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
16363137	Thermo Scientific™ 42105-259270A	250 mm	20 mm	5 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
16373137	Thermo Scientific™ 42110-104630	100 mm	4.6 mm	10 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
16383137	Thermo Scientific™ 42110-154630	150 mm	4.6 mm	10 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
16393137	Thermo Scientific™ 42110-254630	250 mm	4.6 mm	10 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
16303147	Thermo Scientific™ 42110-259070A	250 mm	10 mm	10 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
16313147	Thermo Scientific™ 42110-259270A	250 mm	20 mm	10 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
16323147	Thermo Scientific™ 42203-104630	100 mm	4.6 mm	3 μm	Tris-(4-Methylbenzoyl)-Cellulose
16333147	Thermo Scientific™ 42203-154630	150 mm	4.6 mm	3 μm	Tris-(4-Methylbenzoyl)-Cellulose
16343147	Thermo Scientific™ 42203-254630	250 mm	4.6 mm	3 μm	Tris-(4-Methylbenzoyl)-Cellulose
16353147	Thermo Scientific™ 42205-104630	100 mm	4.6 mm	5 μm	Tris-(4-Methylbenzoyl)-Cellulose
16363147	Thermo Scientific™ 42205-154630	150 mm	4.6 mm	5 μm	Tris-(4-Methylbenzoyl)-Cellulose
16373147	Thermo Scientific™ 42205-254630	250 mm	4.6 mm	5 μm	Tris-(4-Methylbenzoyl)-Cellulose
16383147	Thermo Scientific™ 42205-259070A	250 mm	10 mm	5 μm	Tris-(4-Methylbenzoyl)-Cellulose
16393147	Thermo Scientific™ 42210-104630	100 mm	4.6 mm	10 μm	Tris-(4-Methylbenzoyl)-Cellulose
16303157	Thermo Scientific™ 42210-154630	150 mm	4.6 mm	10 μm	Tris-(4-Methylbenzoyl)-Cellulose
16313157	Thermo Scientific™ 42210-254630	250 mm	4.6 mm	10 μm	Tris-(4-Methylbenzoyl)-Cellulose
16323157	Thermo Scientific™ 42210-259070A	250 mm	10 mm	10 μm	Tris-(4-Methylbenzoyl)-Cellulose

Description

Separate a wide range of enantiomers with Thermo Scientific™ Hypersil™ Chiral HPLC columns, designed for separations of neutral, acidic and basic racemates in normal phase. These chiral columns can help ensure your purification needs are met by resolving racemic mixtures and potential contaminants so you can be confident in the purity of your target compound. To maximize screening efficiency, these columns can be ordered in kits which contain a column in each of our chiral phases. All columns are available in analytical and preparative scale formats.

Separate Enantiomers

Hypersil Chiral JT

• Best starting point for method development.
• Chemistry: Tris-(4-methylbenzoyl)-cellulose modified silica.
• USP L80.

Hypersil Chiral AT

• Highest generality of all chiral phases.
• No aromatic ring necessary.
• No inversion of elution order possible.
• Chemistry: Amylose tris-3,5-dimethylphenylcarbamate modified silica.
• USP L51.

Hypersil Chiral OT

• Highly versatile chiral phases.
• No aromatic ring necessary.
• No inversion of elution order possible.
• Chemistry: Cellulose tris-(3.5-dimethylphenyl-carbamate) modified silica.
• USP L40.

Chiral Column Kits

• Contain three columns, one of each Hypersil Chiral JT, Hypersil Chiral AT, and Hypersil Chiral OT.

HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs.

Standard Threaded and Standard Flange Hardware

• Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use.
• Standard threaded hardware for column i.d. < 40mm.
• Standard flange hardware for column i.d. ≥ 40mm.
• Standard hardware can be modified on request to be compatible with SFC.

Customer Specific Orders

• There are many other Chiral Stationary Phases (CSP’S) available from Thermo Scientific including immobilized brush-type phases. If there is a Thermo Scientific stationary phase you are currently using and would like to obtain in preparative scale or would like to discuss a specific phase that is not listed above, we would be happy to discuss your requirements.
• Please contact your local sales representative for Customer Specific Orders.
• Custom built columns are not eligible for returns.

Specifications

• Column Format: Preparative Column and Analytical Column, Standard
• Pore Size: 1000 Å
• Temperature: Room Temperature

• Max. Pressure: 3700 psi (255 bar)
• Surface Area: 30 m²/g
• Packing Material: Spherical, Fully Porous Silica