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Isopropylidene malonate, 97%, Thermo Scientific Chemicals
£31.70 - £347.00
Chemical Identifiers
CAS | 2033-24-1 |
---|---|
Molecular Formula | C6H8O4 |
Molecular Weight (g/mol) | 144.126 |
MDL Number | MFCD00006638 |
InChI Key | GXHFUVWIGNLZSC-UHFFFAOYSA-N |
Synonym | meldrum's acid, isopropylidene malonate, meldrums acid, 1,3-dioxane-4,6-dione, 2,2-dimethyl, sub-isopropyl malonate, 2,2-dimethyl-1,3-dioxan-4,6-dione, cycl-isopropylidene malonate, cyclic isopropylidene malonate, malonic acid cyclic isopropylidene ester, meldrum acid |
PubChem CID | 16249 |
IUPAC Name | 2,2-dimethyl-1,3-dioxane-4,6-dione |
SMILES | CC1(OC(=O)CC(=O)O1)C |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
11477467
|
Thermo Scientific Alfa Aesar
A15603.14 |
25 g |
£31.70
25g |
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11487467
|
Thermo Scientific Alfa Aesar
A15603.22 |
100 g |
£87.00
100g |
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11497467
|
Thermo Scientific Alfa Aesar
A15603.36 |
500 g |
£347.00
500g |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Isopropylidene malonate is an important reagent in synthetic chemistry and involved in the formation of new C-C bonds, rings, amides, esters, and acids. The presence of carbonyl groups at C-4 and C-6 positions favors the alkylation and acylation reactions due to its acidic nature. It is also employed as an antimicrobial agent. It is used in the preparation of 4-pyridyl-substituted heterocycles, 2-substituted indoles, isofraxidin and macrocyclic beta-keto lactones. Further, it is involved in the Knoevenagel condensation reaction with aldehydes.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsIsopropylidene malonate is an important reagent in synthetic chemistry and involved in the formation of new C-C bonds, rings, amides, esters, and acids. The presence of carbonyl groups at C-4 and C-6 positions favors the alkylation and acylation reactions due to its acidic nature. It is also employed as an antimicrobial agent. It is used in the preparation of 4-pyridyl-substituted heterocycles, 2-substituted indoles, isofraxidin and macrocyclic beta-keto lactones. Further, it is involved in the Knoevenagel condensation reaction with aldehydes.
Solubility
Soluble in water. Slightly soluble in ethanol and chloroform.
Notes
Store in a cool place. Incompatible with strong oxidizing agents.
Chemical Identifiers
2033-24-1 | |
144.126 | |
GXHFUVWIGNLZSC-UHFFFAOYSA-N | |
16249 | |
CC1(OC(=O)CC(=O)O1)C |
C6H8O4 | |
MFCD00006638 | |
meldrum's acid, isopropylidene malonate, meldrums acid, 1,3-dioxane-4,6-dione, 2,2-dimethyl, sub-isopropyl malonate, 2,2-dimethyl-1,3-dioxan-4,6-dione, cycl-isopropylidene malonate, cyclic isopropylidene malonate, malonic acid cyclic isopropylidene ester, meldrum acid | |
2,2-dimethyl-1,3-dioxane-4,6-dione |
Specifications
2033-24-1 | |
C6H8O4 | |
117310 | |
14,5817 | |
Soluble in water. Slightly soluble in ethanol and chloroform. | |
CC1(OC(=O)CC(=O)O1)C | |
144.126 | |
144.13 | |
Isopropylidene malonate |
92°C to 96°C | |
MFCD00006638 | |
Moisture sensitive | |
meldrum's acid, isopropylidene malonate, meldrums acid, 1,3-dioxane-4,6-dione, 2,2-dimethyl, sub-isopropyl malonate, 2,2-dimethyl-1,3-dioxan-4,6-dione, cycl-isopropylidene malonate, cyclic isopropylidene malonate, malonic acid cyclic isopropylidene ester, meldrum acid | |
GXHFUVWIGNLZSC-UHFFFAOYSA-N | |
2,2-dimethyl-1,3-dioxane-4,6-dione | |
16249 | |
98% |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362
H315
missing translation for 'dotInformation' : Hazard Class: 9; Packaging Group: III
missing translation for 'einecsNumber' : 217-992-8
missing translation for 'rtecsNumber' : JH0800000
missing translation for 'tsca' : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only