Thermo Scientific Chemicals Kanamycin sulfate

Description

Kanamycin sulfate, CAS # 25389-94-0, is an aminoglycoside sulfate salt with antibacterial activity.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Kanamycin sulfate is the sulfate salt form of kanamycin A
• It was isolated from Streptomyces kanamyceticus
• This compound inhibits translocation during protein biosynthesis. It binds to the 30S ribosomal subunit, causing misreading of the mRNA sequence

Application

• Kanamycin sulfate shows antibacterial activity. It is effective against gram-positive and gram-negative bacteria, as well as Mycoplasma species
• This compound is also involved in translating prokaryotic ribosomes
• In molecular biology experiments, it is commonly used to select and isolate transformants expressing the kanamycin resistance gene, and plants that have the NPT II (APH3) gene incorporated

Specifications

Chemical Identifiers

• CAS: 25389-94-0
• Molecular Formula: C18H38N4O15S
• Molecular Weight (g/mol): 582.575
• MDL Number: MFCD00070253
• InChI Key: OOYGSFOGFJDDHP-IZQIRFRQSA-N
• PubChem CID: 134129479
• IUPAC Name: (2R,3S,4S,5S,6R)-2-(aminomethyl)-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5R,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acid
• SMILES: C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N.OS(=O)(=O)O

• Type: Kanamycin Sulfate
• Packaging: Glass Bottle
• Quantity: 10 g
• Solubility Information: Solubility in water: soluble.
• Formula Weight: 582.59
• Chemical Name or Material: Kanamycin sulfate

Safety and Handling

Product Identifier

• Kanamycin Sulfate

Signal Word

• Danger

Hazard Category

• Reproductive toxicity Category 1B
• Respiratory sensitiser Category 1
• Skin sensitiser Category 1

Hazard Statement

• H317-May cause an allergic skin reaction.
• H360FD-May damage fertility. May damage the unborn child.
• H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Precautionary Statement

• P201-Obtain special instructions before use.
• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P308+P313-IF exposed or concerned: Get medical advice/attention.
• P342+P311-If experiencing respiratory symptoms: Call a POISON CENTER/doctor/ .

RUO – Research Use Only