L-Proline, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11439512	Thermo Scientific Alfa Aesar A10199.14	25 g
11449512	Thermo Scientific Alfa Aesar A10199.22	100 g
11459512	Thermo Scientific Alfa Aesar A10199.36	500 g

Description

L-Proline is used as asymmetric catalysts in organic synthesis and asymmetric aldol cyclization. It is involved in the Michael addition of dimethyl malonate to alfa-beta-unsaturated aldehydes. It is a precursor of hydroxyproline in collagen. It is an active component of collagen and involved in the proper functioning of joints and tendons. It finds uses in pharmaceutical, biotechnological applications due to its osmoprotectant property. Further, it is used with ninhydrin in the chromatography.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
L-Proline is used as asymmetric catalysts in organic synthesis and asymmetric aldol cyclization. It is involved in the Michael addition of dimethyl malonate to alfa-beta-unsaturated aldehydes. It is a precursor of hydroxyproline in collagen. It is an active component of collagen and involved in the proper functioning of joints and tendons. It finds uses in pharmaceutical, biotechnological applications due to its osmoprotectant property. Further, it is used with ninhydrin in the chromatography.

Solubility
Soluble in water and ethanol. Insoluble in ether, butanol and isopropanol.

Notes
Hygroscopic. Incompatible with strong oxidizing agents.

Chemical Identifiers

• CAS: 147-85-3
• Molecular Weight (g/mol): 115.13
• InChI Key: ONIBWKKTOPOVIA-UHFFFAOYNA-N
• PubChem CID: 145742
• IUPAC Name: (2S)-pyrrolidine-2-carboxylic acid

• Molecular Formula: C5H9NO2
• MDL Number: MFCD00064318
• Synonym: l-proline, proline, l---proline, s-pyrrolidine-2-carboxylic acid, 2-pyrrolidinecarboxylic acid, --proline, --s-proline, 2s-pyrrolidine-2-carboxylic acid, prolinum, h-pro-oh
• ChEBI: CHEBI:17203
• SMILES: OC(=O)C1CCCN1

Specifications

• Melting Point: ∽225°C (decomposition)
• Molecular Formula: C5H9NO2
• Beilstein: 80810
• Solubility Information: Soluble in water and ethanol. Insoluble in ether,butanol and isopropanol.
• Density: 1.36
• IUPAC Name: (2S)-pyrrolidine-2-carboxylic acid
• PubChem CID: 145742
• Formula Weight: 115.13
• Chemical Name or Material: L-Proline

• CAS: 147-85-3
• MDL Number: MFCD00064318
• Synonym: l-proline, proline, l---proline, s-pyrrolidine-2-carboxylic acid, 2-pyrrolidinecarboxylic acid, --proline, --s-proline, 2s-pyrrolidine-2-carboxylic acid, prolinum, h-pro-oh
• InChI Key: ONIBWKKTOPOVIA-UHFFFAOYNA-N
• SMILES: OC(=O)C1CCCN1
• Molecular Weight (g/mol): 115.13
• ChEBI: CHEBI:17203
• Sensitivity: Hygroscopic

Safety and Handling

missing translation for 'einecsNumber' : 205-702-2

missing translation for 'rtecsNumber' : TW3584000

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

RUO – Research Use Only