Estrogen Receptor (SP1) Rabbit Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Epredia™ Estrogen Receptor (SP1), Rabbit Monoclonal Antibody.

Product Code	Brand	Form	Quantity
12623667	Epredia RM-9101-S0	Concentrated	100 μL
12643667	Epredia RM-9101-S1	Concentrated	500 μL
10773394	Epredia RM-9101-S	Concentrated	1 mL
12683657	Epredia RM-9101-R7	Prediluted	7 mL
12613667	Epredia RM-9101-RQ	Ready-to-Use	12 mL

Description

Recognizes a protein of 67 kDa, which is identified as estrogen receptor (ER) alpha. The ER gene consists of more than 140kb of genomic DNA divided into 8 exons, and is translated into a protein with six functionally discrete domains, labeled A through F. This antibody strongly stains the nucleus of epithelial cells in breast carcinomas. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Rabbit

Clone: SP1

Isotype: IgG

Species Reactivity: Human, Mouse and Hamster. Others not tested.

Epitope: C-terminus

Immunogen: Synthetic peptide derived from C-terminal of human estrogen receptor

Molecular Weight: 67 kDa

Positive Control: Breast CA, MCF-7 cells

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunofluorescence (Not verified)
• Flow Cytometery (Not verified)

Specifications

• Antigen: Estrogen Receptor (SP1)
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Host Species: Rabbit
• Research Discipline: Steroids Hormones and Growth Factors
• Primary or Secondary: Primary

• Clone: SP1
• Classification: Monoclonal
• Regulatory Status: IVD
• Immunogen: Synthetic peptide derived from C-terminal of human estrogen receptor