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Tocris Bioscience™ NSC 23766
Selective inhibitor of Rac1-GEF interaction; antioncogenic
£162.00 - £600.00
Specifications
| Product Type | NSC 23766 |
|---|---|
| Molecular Weight (g/mol) | 530.97 |
| Inhibitors | Rho GTPase Inhibitors |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18765346
|
Tocris Bioscience™
2161/10 |
10 mg |
£162.00
10mg |
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|
18014632
|
Tocris Bioscience™
2161/50 |
50 mg |
£600.00
50mg |
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Description
Selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC50 ∽ 50 μM) without affecting Cdc42 or RhoA activation. Inhibits Rac1-mediated cell functions and is reported to reverse tumor cell phenotypes in prostate cancer cells.Specifications
| NSC 23766 | |
| 530.97 | |
| Rho GTPase Inhibitors |
For Research Use Only