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PF 04671536 hydrochloride
Potent and selective PDE8B/8A inhibitor
Brand: Tocris 6024/5
Additional Details : Weight : 0.00970kg
Description
PF 04671536 hydrochloride is a potent and selective PDE8B/8A inhibitor (IC50 values are 1.3 and 1.9 nM, respectively). Exhibits selectivity for PDE8A/B over other PDEs (IC50 values are >10 μM) and a range of other targets. Increases glucose-dependent insulin secretion from human pacreatic islet cells. Orally bioavailable.Specifications
5-Methyl-3-[[(2R)-4-(2-thiazolylmethyl)-2-morpholinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine hydrochloride | |
>98% | |
C14H18N8OS.HCl |
1305116-67-9 | |
5 mg | |
Observed MW: 382.87 |