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PF 04671536 hydrochloride
Potent and selective PDE8B/8A inhibitor
£94.00 - £343.00
Specifications
Chemical Name or Material | 5-Methyl-3-[[(2R)-4-(2-thiazolylmethyl)-2-morpholinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine hydrochloride |
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CAS | 1305116-67-9 |
Assay Percent Range | >98% |
Molecular Formula | C14H18N8OS.HCl |
Formula Weight | Observed MW: 382.87 |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
18777108
|
Tocris Bioscience
6024/25 |
25 mg |
£343.00
25mg |
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18766378
|
Tocris Bioscience
6024/5 |
5 mg |
£94.00
5mg |
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Description
Potent and selective PDE8B/8A inhibitor ( IC50 values are 1.3 and 1.9 nM, respectively). Exhibits selectivity for PDE8A/B over other PDEs (IC50 values are >10 μM) and a range of other targets. Increases glucose-dependent insulin secretion from human pacreatic islet cells. Orally bioavailable.Specifications
5-Methyl-3-[[(2R)-4-(2-thiazolylmethyl)-2-morpholinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine hydrochloride | |
>98% | |
Observed MW: 382.87 |
1305116-67-9 | |
C14H18N8OS.HCl |
Safety and Handling
Recommended Storage : Desiccate at Room Temperature