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PF 04671536 hydrochloride

Potent and selective PDE8B/8A inhibitor

Brand:  Tocris Bioscience 6024/25

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Product Code. 18777108

  • £343.00 / 25mg

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Description

Description

PF 04671536 hydrochloride is a potent and selective PDE8B/8A inhibitor (IC50 values are 1.3 and 1.9 nM, respectively). Exhibits selectivity for PDE8A/B over other PDEs (IC50 values are >10 μM) and a range of other targets. Increases glucose-dependent insulin secretion from human pacreatic islet cells. Orally bioavailable.
Specifications

Specifications

5-Methyl-3-[[(2R)-4-(2-thiazolylmethyl)-2-morpholinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine hydrochloride
>98%
C14H18N8OS.HCl
1305116-67-9
25 mg
Observed MW: 382.87
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