Thermo Scientific™ Pierce™ Alkylating Reagents

Alkylating reagents provided in single-use, pre-weighed formats to streamline protein preparation workflows.

Brand:  Thermo Scientific™ A39271

Product Code. 15940677

Description

Thermo Scientific Pierce Iodoacetamide or Chloroacetamide are provided in a no-weigh format, where small amounts of reagent are pre-weighed and packaged for single use. This single-use format prevents the contamination and loss of reagent reactivity over time associated with repetitive opening and closing of a single vial. The format enables use of a fresh vial of reagent each time, and eliminates the hassle of weighing out small amounts of reagent.

Alkylating reagents iodoacetamide and chloracetamide are sulfhydryl-reactive alkylating reagents used to block reduced cysteine residues for protein characterization and peptide mapping. Alkylation with iodoacetamide or chloracetamide after cysteine reduction results in the covalent addition of a carbamidomethyl group (57.07 Da) and prevents the formation of disulfide bonds. Reducing agents added after alkylation will react with excess iodoacetamide.

Specifications

• Product Type: Alkylating Reagent
• Quantity: 30 x 9.3 mg
• Includes: Iodoacetamide
• Product Line: Pierce™

Safety and Handling

Product Identifier

• Pierce Iodoacetamide, No-Weigh Format

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• Respiratory sensitiser Category 1
• Skin sensitiser Category 1

Hazard Statement

• H301-Toxic if swallowed.
• H317-May cause an allergic skin reaction.
• H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Precautionary Statement

• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P264-Wash hands thoroughly after handling.
• P270-Do not eat, drink or smoke when using this product.
• P272-Contaminated work clothing should not be allowed out of the workplace.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P308+P313-IF exposed or concerned: Get medical advice/attention.
• P330-Rinse mouth.
• P333+P313-If skin irritation or rash occurs: Get medical advice/attention.
• P363-Wash contaminated clothing before reuse.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information

• MIXTURE LIST-Contains : 2-Iodoacetamide