Thermo Scientific™ DMP (dimethyl pimelimidate)

Crosslink amines to amines with dimethyl pimelimidate (CAS 58537-94-3); composed of imidoester groups and a membrane-permeable, 7-atom spacer arm.

Brand:  Thermo Scientific™ 21666

Product Code. 10097093

Description

Thermo Scientific™ Pierce DMP is dimethyl pimelimidate, a membrane-permeable crosslinker that contains an amine-reactive imidoester group at each end of a 7-atom spacer arm.

Highlights:

• Water-soluble
• Rapid reaction with amines at alkaline pH values (pH 8-10)
• Amidine bond retains net charge character of protein
• Reversible at high pH values
• Reactive groups: imidoester (homobifunctional)
• Reactive toward: amino groups

Specifications

• Chemical Reactivity: Amine-Amine
• Description: DMP
• PEGylated: No
• Content And Storage: Upon receipt store desiccated at 4°C.
• Shipping Condition: Ambient
• Labeling Method: Chemical Labeling
• Reactive Moiety: Imidoester
• Form: Powder
• Solubility: Water
• Water Soluble: Yes

• Cleavable: No
• Molecular Weight (g/mol): 259.17
• Spacer Arm Length: 9.2 Å
• Cell Permeability: Yes
• Product Line: Pierce™
• Crosslinker Type: Homobifunctional
• Spacer: Short (<10 Å)
• Quantity: 50 mg
• Format: Standard
• Product Type: Crosslinker

Safety and Handling

Product Identifier

• DMP (dimethyl pimelimidate)

Signal Word

• Warning

Hazard Category

• Skin corrosion/irritation Category 2

Hazard Statement

• H315-Causes skin irritation.

Precautionary Statement

• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P264-Wash hands thoroughly after handling.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Supplemental information

• MIXTURE LIST-Contains : dimethyl heptane-1,7-diimidate dihydrochloride

For Research Use Only. Not for use in diagnostic procedures.