Thermo Scientific™ Pierce™ TCEP-HCl, No-Weigh™ Format

Reduce protein and peptide disulfide bonds using this thiol-free, pure, crystalline tris (2-carboxyethyl) phosphine hydrochloride, TCEP (CAS 5961-85-3).

Product Code	Brand	Quantity
10530434	Thermo Scientific™ 20490	1 g
11856784	Thermo Scientific™ 20491	10 g
15780329	Thermo Scientific™ A35349	10 x 1 mg

Description

Thermo Scientific™ Pierce TCEP-HCl is pure, crystalline Tris(2-carboxyethyl)phosphine hydrochloride, a thiol-free compound that is highly effective at reducing protein and peptide disulfide bonds, as well as being odorless and stable.

Highlights:

• Reduces even the most stable water-soluble alkyl disulfides
• Effective at room temperature and pH 5 in less than five minutes
• Does not require removal before reaction with maleimide or haloacetyl compounds
• Water solubility of 310g/L
• Resistant to air oxidation; nonvolatile and nonreactive toward other functional groups in proteins

Specifications

• Form: Solid

Safety and Handling

Product Identifier

• TCEP HCl, Tris(2-Carboxyethyl) Phosphine Hydrochloride

Signal Word

• Danger

Hazard Category

• Serious eye damage/eye irritation Category 1
• Skin corrosion/irritation Category 1 B

Hazard Statement

• H314-Causes severe skin burns and eye damage.

Precautionary Statement

• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.

Supplemental information

• MIXTURE LIST-Contains : Tris(2-carboxyethyl)phosphonium chloride

For Research Use Only. Not for use in diagnostic procedures.