missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Tocris Bioscience™ Pyr 10
Selective TRPC3 inhibitor
£128.51 - £477.31
Specifications
| Chemical Name or Material | N-[4-[3,5-bis(Trifluoromethyl)-1 H-pyrazol-1-yl]phenyl]-4-methylbenzenesulfonamide |
|---|---|
| CAS | 1315323-00-2 |
| Target | TRPC Channel Blockers |
| Molecular Formula | C18H13F6N3O2S |
| Purity | 0.98 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18758536
|
Tocris Bioscience™
6941/10 |
10 mg |
£128.51
10mg |
Estimated Shipment: 30-07-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
18768946
|
Tocris Bioscience™
6941/50 |
50 mg |
£477.31
50mg |
Estimated Shipment: 30-07-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Pyr 10 is a TRPC3 (transient receptor potential canonical 3) channel inhibitor (IC50 = 0.72 μM for TRPC3 mediated calcium entry in vitro), which displays approximately 18-fold selectivity for TRPC3-mediated receptor operated calcium entry (ROCE) over STIM1/Orai1-mediated store operated calcium entry (SOCE). Pyr 10 inhibits NFATc3 activation and inhibits proliferation of rat ventricular cardiac fibroblasts.Specifications
| N-[4-[3,5-bis(Trifluoromethyl)-1 H-pyrazol-1-yl]phenyl]-4-methylbenzenesulfonamide | |
| TRPC Channel Blockers | |
| 0.98 |
| 1315323-00-2 | |
| C18H13F6N3O2S |