Tocris Bioscience™ Pyridostatin pentahydrochloride

Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest

Brand:  Tocris Bioscience™ 4763/10

Product Code. 18744719

Description

Binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM); targets the proto-oncogene Src, reducing Src protein abundance and Src-dependent motility in human breast cancer cells. Also targets telomeric G-quadruplexes, inducing telomerase dysfunction. Activates the DNA-dependent protein kinase catalytic sunbunit (DNA-PKcs).

Specifications

• Purity: 95%
• CAS: 1781882-65-2
• Quantity: 10 mg
• Molecular Weight (g/mol): M.W. (Observed): 778.94

• Molecular Formula: 4-(2-Aminoethoxy)N2,N6-bis[(4-(2-aminoethoxy)-2-quinolinyl]-2,6-pyridinecarboxamide pentahydrochloride
• Content And Storage: Desiccate at RT
• Product Type: Pyridostatin pentahydrochloride
• Inhibitors: Pyridostatin pentahydrochloride

For Research Use Only