Tocris Bioscience™ Pyridostatin pentahydrochloride

Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest

Product Code	Brand	Quantity
18744719	Tocris Bioscience™ 4763/10	10 mg

Description

Binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM); targets the proto-oncogene Src, reducing Src protein abundance and Src-dependent motility in human breast cancer cells. Also targets telomeric G-quadruplexes, inducing telomerase dysfunction. Activates the DNA-dependent protein kinase catalytic sunbunit (DNA-PKcs).

Specifications

• CAS: 1781882-65-2
• Product Type: Pyridostatin pentahydrochloride
• Inhibitors: Pyridostatin pentahydrochloride

For Research Use Only