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Gibco™ Rat TPO (Thrombopoietin) Recombinant Protein, PeproTech®
E. coli Recombinant Protein
£65.00 - £3455.00
Specifications
Accession Number | P49745 |
---|---|
For Use With (Application) | Functional Assay |
Formulation | protein with no preservative |
Gene ID (Entrez) | 108348162, 81811 |
Molecular Weight (g/mol) | 18.7 |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17864523
|
Gibco™
400-34-100UG |
100 μg |
£690.00
100µg |
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17803913
|
Gibco™
400-34-10UG |
10 μg |
£158.00
10µg |
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17894383
|
Gibco™
400-34-1MG |
1 mg |
£3455.00
1mg |
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17884383
|
Gibco™
400-34-250UG |
250 μg |
£1210.00
250µg |
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17863833
|
Gibco™
400-34-2UG |
2 μg |
£65.00
2µg |
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17834563
|
Gibco™
400-34-500UG |
500 μg |
£2070.00
500µg |
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Description
Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) is responsible for the generation of platelets through its action on hematopoietic cells committed to the megakaryocyte lineage. Binding of thrombopoietin to its receptor, MPL (CD110), initiates a signaling cascade via JAK/STAT, MAPK, and PI3K/AKT signaling pathways that leads to the proliferation and differentiation of megakaryocytes and, ultimately, to the production of platelets (thrombopoiesis). Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.Specifications
P49745 | |
protein with no preservative | |
18.7 | |
E. coli | |
RUO | |
C-mpl ligand; Megakaryocyte colony-stimulating factor; megakaryocyte growth and development factor; megakaryocyte stimulating factor; Mgdf; MKCSF; ML; MPL ligand; Mpllg; MSA; Myeloproliferative leukemia virus oncogene ligand; prepro-thrombopoietin; TDH2A; THCYT1; THPO; Thrombopoietin; thyroid microsomal antigen; thyroid peroxidase; thyroperoxidase; Tpo; TPX | |
Rat | |
Recombinant | |
Lyophilized |
Functional Assay | |
108348162, 81811 | |
Rat TPO (Thrombopoietin) | |
-20°C | |
<1 EU/μg | |
THPO | |
Unconjugated | |
SPVPPACDPR LLNKLLRDSY LLHSRLSQCP DVNPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPPQGRTTA HKDPSALFLS LQQLLRGKVR FLLLVEGPAL CVRRTLPTTA VPSRTSQLLT LNKF | |
≥ 98% by SDS-PAGE gel and HPLC analyses. |