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Gibco™ Rat TPO (Thrombopoietin) Recombinant Protein, PeproTech®

E. coli Recombinant Protein

£65.00 - £3455.00

Specifications

Accession Number P49745
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 108348162, 81811
Molecular Weight (g/mol) 18.7
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Products 6
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17864523
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Gibco™
400-34-100UG
100 μg
£690.00
100µg
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17803913
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Gibco™
400-34-10UG
10 μg
£158.00
10µg
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17894383
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Gibco™
400-34-1MG
1 mg
£3455.00
1mg
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17884383
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Gibco™
400-34-250UG
250 μg
£1210.00
250µg
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17863833
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Gibco™
400-34-2UG
2 μg
£65.00
2µg
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17834563
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Gibco™
400-34-500UG
500 μg
£2070.00
500µg
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Description

Description

Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) is responsible for the generation of platelets through its action on hematopoietic cells committed to the megakaryocyte lineage. Binding of thrombopoietin to its receptor, MPL (CD110), initiates a signaling cascade via JAK/STAT, MAPK, and PI3K/AKT signaling pathways that leads to the proliferation and differentiation of megakaryocytes and, ultimately, to the production of platelets (thrombopoiesis). Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.
Specifications

Specifications

P49745
protein with no preservative
18.7
E. coli
RUO
C-mpl ligand; Megakaryocyte colony-stimulating factor; megakaryocyte growth and development factor; megakaryocyte stimulating factor; Mgdf; MKCSF; ML; MPL ligand; Mpllg; MSA; Myeloproliferative leukemia virus oncogene ligand; prepro-thrombopoietin; TDH2A; THCYT1; THPO; Thrombopoietin; thyroid microsomal antigen; thyroid peroxidase; thyroperoxidase; Tpo; TPX
Rat
Recombinant
Lyophilized
Functional Assay
108348162, 81811
Rat TPO (Thrombopoietin)
-20°C
<1 EU/μg
THPO
Unconjugated
SPVPPACDPR LLNKLLRDSY LLHSRLSQCP DVNPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPPQGRTTA HKDPSALFLS LQQLLRGKVR FLLLVEGPAL CVRRTLPTTA VPSRTSQLLT LNKF
≥ 98% by SDS-PAGE gel and HPLC analyses.
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