Tocris Bioscience™ Rhosin hydrochloride

Rho GTPase inhibitor

Brand:  Tocris Bioscience™ 5003/10

Product Code. 18798718

Description

Rhosin hydrochloride is a Rho GTPase inhibitor (Kd = 354 nM). Inhibits binding of RhoA to guanine nucleotide exchange factors (GEFs) including LARG, DBL, LBC, p115 RhoGEF and PDZ RhoGEF. Has no effect on the binding of Rac1 or Cdc42 to their respective GEFs. Suppresses RhoA/C-mediated breast cancer cell migration and invasion in vitro. Also induces neurite outgrowth in synergy with NGF.

Specifications

• Purity: >98%
• Product Type: Rhosin hydrochloride
• Inhibitors: Rho GTPase Inhibitors

• Quantity: 10 mg
• Molecular Weight (g/mol): 394.86

For Research Use Only