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Tocris Bioscience™ Ro 25-6981 maleate

GluN2B-selective NMDA antagonist

Brand:  Tocris Bioscience™ 1594/10

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Product Code. 18795866

  • £175.00 / 10mg

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Description

Description

Ro 25-6981 maleate is a potent and selective activity-dependent blocker of NMDA receptors containing the GluN2B (formally NR2B) subunit. IC50 values are 0.009 and 52 μM for cloned receptor subunit combinations GluN1C/GluN2B and GluN1C/GluN2A respectively. Displays neuroprotectant effects in vivo and in vitro.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Specifications

Specifications

(αR,βS)-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate
>98%
Soluble to 100mM in DMSO
Observed MW: 455.55
1312991-76-6
10 mg
C22H29NO2.C4H4O4
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