Selpercatinib, MedChemExpress

MedChemExpress Selpercatinib (LOXO-292) is a potent, selective RET kinase inhibitor with IC50 values of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M), and RET (G810R), respectively. Selpercatinib has anticancer activity.

Brand:  Medchem Express HY-114370

Product Code. 16411087

Description

Selpercatinib (LOXO-292) is a potent, selective RET kinase inhibitor with IC50 values of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M), and RET (G810R), respectively. Selpercatinib has anticancer activity.

Specifications

• Chemical Name or Material: Selpercatinib
• Color: White
• Molecular Formula: C₂₉H₃₁N₇O₃
• Synonym: LOXO-292
• SMILES: N#CC1=C2C(C3=CC=C(N4CC(C5)N(CC6=CC=C(OC)N=C6)C5C4)N=C3)=CC(OCC(C)(O)C)=CN2N=C1
• Formula Weight: 525.6
• Grade: Research
• For Use With (Application): Cancer-Kinase/protease

• CAS: 2152628-33-4
• Purity Grade Notes: Research
• Quantity: 50 mg
• Solubility Information: DMSO : 62.5 mg/mL (118.91 mM; Need ultrasonic)
• Molecular Weight (g/mol): 525.6
• Percent Purity: 98.06%
• Physical Form: Solid

Research purposes only