Selpercatinib, MedChemExpress

MedChemExpress Selpercatinib (LOXO-292) is a potent, selective RET kinase inhibitor with IC50 values of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M), and RET (G810R), respectively. Selpercatinib has anticancer activity.

Product Code	Brand	Quantity
16474818	Medchem Express HY-114370	10 mg
16467567	Medchem Express HY-114370	5 mg
16455616	Medchem Express HY-114370	100 mg
16411087	Medchem Express HY-114370	50 mg

Description

Selpercatinib (LOXO-292) is a potent, selective RET kinase inhibitor with IC50 values of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M), and RET (G810R), respectively. Selpercatinib has anticancer activity.

Specifications

• Chemical Name or Material: Selpercatinib
• Color: White
• Molecular Formula: C₂₉H₃₁N₇O₃
• Solubility Information: DMSO : 62.5 mg/mL (118.91 mM; Need ultrasonic)
• Molecular Weight (g/mol): 525.6
• Percent Purity: 98.06%
• Physical Form: Solid

• CAS: 2152628-33-4
• Purity Grade Notes: Research
• Synonym: LOXO-292
• SMILES: N#CC1=C2C(C3=CC=C(N4CC(C5)N(CC6=CC=C(OC)N=C6)C5C4)N=C3)=CC(OCC(C)(O)C)=CN2N=C1
• Formula Weight: 525.6
• Grade: Research
• For Use With (Application): Cancer-Kinase/protease

Safety and Handling

missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

Research purposes only