Tocris Bioscience™ SGC 707

Potent and selective allosteric inhibitor of PRMT3

Product Code	Brand	Quantity
18762138	Tocris Bioscience™ 5367/10	10 mg
18759917	Tocris Bioscience™ 5367/50	50 mg

Description

SGC 707 is a potent allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) (IC50 = 31 nM). Inhibits PRMT3-mediated methyltransferase activity in vitro. Displays >100-fold selectivity against 31 other methyltransferases and 250 other non-epigenetic targets. Decreases H4R3me2a levels in HEK293 cells in vitro.

Negative control also available.

Specifications

• Purity: >98%
• Product Type: SGC 707
• Molecular Weight (g/mol): 298.34
• Inhibitors: SGC 707

For Research Use Only