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Eurofins DiscoverX SGK1 (S422D) Protein, Unactive
Unactive, N-truncated (missing N-terminal 59 amino acids), N-terminal 6His-tagged, human SGK1 fusion protein, containing an S422D mutation, for use in Kinase Assays.
£448.44 - £3422.71
Specifications
Formulation | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 0.1 mM EGTA, 150 mM NaCl, 0.03% Brij-35, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol, 270 mM sucrose. Frozen solution. |
---|---|
Molecular Weight (g/mol) | 45.7 kDa |
Species | Human |
Recombinant | Recombinant |
Protein Tag | N-terminal 6His |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17320144
|
Eurofins DiscoverX
14-332 |
25 μg |
£448.44
25µg |
Estimated Shipment: 15-08-2024 Log in to see stock. |
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17330144
|
Eurofins DiscoverX
14-332M |
250 μg |
£3422.71
250µg |
Estimated Shipment: 15-08-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
The serum/glucocorticoid regulated kinases (SGK1,2,3) are serine/threonine kinases that belong to the AGC (protein kinase A; protein kinase G and protein kinase C) subfamily that includes cAMP and cGMP dependent kinases, PKB and PKC. SGK1 (SGK) is predominately expressed in kidney, liver and pancreas. The catalytic domain of serum/glucocorticoid regulated protein kinase is most similar to PKB and activated via phosphorlation mechanism when cells are stimulated with insulin, IGF1 or serum, or exposed to oxidative stress.
GenBank AF153609
Specifications
mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 0.1 mM EGTA, 150 mM NaCl, 0.03% Brij-35, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol, 270 mM sucrose. Frozen solution. | |
Human | |
N-terminal 6His | |
Truncated | |
SGK1 (S422D), unactive |
45.7 kDa | |
Recombinant | |
Recombinant enzyme expressed in Sf21 insect cells | |
≥73% |