Invitrogen™ Tango™ CCR2-bla U2OS Cells

Tango™ CCR2-bla U2OS cells

Brand:  Invitrogen™ K1809

Product Code. 10145223

Description

The Tango™ CCR2-bla U2OS cells contain the human Chemokine (C-C Motif) Receptor 2 (CCR2) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The Tango™ CCR2-bla U2OS cells are functionally validated for Z' and EC₅₀ concentrations of MCP-1. In addition, Tango™ CCR2-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

Specifications

• Content And Storage: Liquid Nitrogen
• Detection Method: Fluorescent
• Includes: K1809 Tango™ CCR2-bla U2OS cells (LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol). Includes: Tango™ CCR2-bla U2OS cells, Tango™ CCR2-bla U2OS Assay Protocol, Certificate of Analysis
• Sample Type: U2OS

• Description: Tango™ CCR2-bla U2OS Cells, 8 x 106 Cells, U2OS Cell Line, Fluorescent Detection Method, GPCRs Druggable Target, BLA (Beta-Lactamase) Reporter, Liquid Nitrogen Storage
• For Use With (Application): Pharma and biopharma, drug discovery and development, target and lead identification and validation, G-protein coupled receptor biology, cell-based GPCR reporter assays
• Quantity: 8 x 106 Cells
• Type: U2OS Cell

For Research Use Only. Not for use in diagnostic procedures.