Tocris Bioscience™ TDZD 8

Selective non-ATP competitive inhibitor of GSK 3β

Brand:  Tocris Bioscience™ 6092/10

Product Code. 18719508

Description

TDZD 8 is a selective non-ATP competitive inhibitor of GSK 3β (IC50 = 2 μM); thiadiazolidinone deriviative. Does not inhibit Cdk-1/cyclin B, CK-II, PKA or PKC at >100 μM. Reduces severity of L-dopa-induced dyskinesia in a Parkinson's disease in vivo model.

Specifications

• Color: White
• CAS: 327036-89-5
• Formula Weight: 222.26g/mol
• Solubility: Soluble to 100mM in DMSO, 100mM in ethanol
• For Use With (Application): Inhibits GSK 3β

• Product Type: Inhibitor
• Molecular Formula: C₁₀H₁₀N₂O₂S
• Synonym: NP 01139
• Content And Storage: Store at -20°C
• Quantity: 10 mg

For Research Use Only