Trichloroacetyl chloride, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11450257	Thermo Scientific Alfa Aesar B21675.18	50 g
11460257	Thermo Scientific Alfa Aesar B21675.30	250 g
11440257	Thermo Scientific Alfa Aesar B21675.0B	1000 g

Description

Trichloroacetyl chloride is used in the preparation of dihydro-1H-benzindoles. It is also used in the synthesis of 3-alkylbenzoxazolones It is used in the manufacture of pharmaceuticals and plant protection compounds. It is used for manufacturing the esters and anhydrides of trichloroacetic acid. It is used in the manufacture of pharmaceuticals and organic synthesis intermediate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trichloroacetyl chloride is used in the preparation of dihydro-1H-benzindoles. It is also used in the synthesis of 3-alkylbenzoxazolones It is used in the manufacture of pharmaceuticals and plant protection compounds. It is used for manufacturing the esters and anhydrides of trichloroacetic acid. It is used in the manufacture of pharmaceuticals and organic synthesis intermediate.

Solubility
Reacts violently with water.

Notes
Moisture sensitive. Store away from oxidizing agents, bases, alcohols, amines and water/moisture. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Chemical Identifiers

• CAS: 76-02-8
• Molecular Weight (g/mol): 181.821
• InChI Key: PVFOMCVHYWHZJE-UHFFFAOYSA-N
• PubChem CID: 6420
• SMILES: C(=O)(C(Cl)(Cl)Cl)Cl

• Molecular Formula: C2Cl4O
• MDL Number: MFCD00000792
• Synonym: trichloroacetyl chloride, superpalite, acetyl chloride, trichloro, trichloroacetochloride, trichloroacetic acid chloride, ccl3cocl, trichloroacetylchloride, unii-9sn86t76y6, ccris 6764, acetyl chloride, 2,2,2-trichloro
• IUPAC Name: 2,2,2-trichloroacetyl chloride

Specifications

• CAS: 76-02-8
• Density: 1.629
• Molecular Formula: C2Cl4O
• MDL Number: MFCD00000792
• Beilstein: 774120
• Synonym: trichloroacetyl chloride, superpalite, acetyl chloride, trichloro, trichloroacetochloride, trichloroacetic acid chloride, ccl3cocl, trichloroacetylchloride, unii-9sn86t76y6, ccris 6764, acetyl chloride, 2,2,2-trichloro
• InChI Key: PVFOMCVHYWHZJE-UHFFFAOYSA-N
• IUPAC Name: 2,2,2-trichloroacetyl chloride
• PubChem CID: 6420
• Percent Purity: 99%

• Melting Point: -146°C
• Boiling Point: 114°C to 116°C
• Refractive Index: 1.47
• UN Number: UN2442
• Sensitivity: Moisture sensitive
• Solubility Information: Reacts violently with water.
• SMILES: C(=O)(C(Cl)(Cl)Cl)Cl
• Molecular Weight (g/mol): 181.821
• Formula Weight: 181.83
• Chemical Name or Material: Trichloroacetyl chloride

Safety and Handling

GHS H Statement
H330-H314-H318-H302
Fatal if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if swallowed.

P260-P264b-P270-P271-P280-P284-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c

H302-H314-H330-H335

missing translation for 'dotInformation' : Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: TRICHLOROACETYL CHLORIDE

missing translation for 'einecsNumber' : 200-926-7

missing translation for 'rtecsNumber' : AO7140000

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures; Store under Argon

Product Identifier

• Trichloroacetyl chloride

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 2
• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 1
• Skin corrosion/irritation Category 1 A

Hazard Statement

• H302-Harmful if swallowed.
• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.
• H330-Fatal if inhaled.
• EUH014-Reacts violently with water.
• EUH029-Contact with water liberates toxic gas.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : Trichloroacetyl chloride

RUO – Research Use Only