(Trifluoromethyl)trimethylsilane, 95%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11434237	Thermo Scientific Alfa Aesar B20347.03	1 g
11444237	Thermo Scientific Alfa Aesar B20347.06	5 g
11454237	Thermo Scientific Alfa Aesar B20347.14	25 g

Description

It is employed as a valuable reagent for trifluoromethylation of electrophilic substrates. It is also use an the nucleophilic addition of the trifluoromethyl group to aldehydes and ketones. It generates trifluoromethide with catalytic amounts of F- (TBAF or CsF) and reacts with carbonyl compounds to produce trifluoromethylated alcohols.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is employed as a valuable reagent for trifluoromethylation of electrophilic substrates. It is also use an the nucleophilic addition of the trifluoromethyl group to aldehydes and ketones. It generates trifluoromethide with catalytic amounts of F- (TBAF or CsF) and reacts with carbonyl compounds to produce trifluoromethylated alcohols.

Solubility
Soluble in alcohol, THF, ether, dichloromethane, aromatic and aliphatic hydrocarbons. Soluble in water(with white smokes).

Notes
Moisture sensitive. Store away from oxidizing agents and water/moisture. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas.

Chemical Identifiers

• CAS: 81290-20-2
• Molecular Weight (g/mol): 156.22
• InChI Key: MTYSDPUZDZURPP-UHFFFAOYSA-N
• PubChem CID: 552549
• SMILES: CC(C)(C)[SiH2]C(F)(F)F

• Molecular Formula: C5H11F3Si
• MDL Number: MFCD00145454
• Synonym: trifluoromethyl trimethylsilane, trimethyl trifluoromethyl silane, trifluoromethyltrimethylsilane, ruppert's reagent, tms-cf3, tfmtms, silane, trimethyl trifluoromethyl, unii-a009786qpj, trimethylsilyl trifluoromethane, ruppert-prakash reagent
• IUPAC Name: trimethyl(trifluoromethyl)silane

Specifications

• Boiling Point: 54°C to 55°C
• Molecular Formula: C5H11F3Si
• MDL Number: MFCD00145454
• Beilstein: 4241868
• Synonym: trifluoromethyl trimethylsilane, trimethyl trifluoromethyl silane, trifluoromethyltrimethylsilane, ruppert's reagent, tms-cf3, tfmtms, silane, trimethyl trifluoromethyl, unii-a009786qpj, trimethylsilyl trifluoromethane, ruppert-prakash reagent
• InChI Key: MTYSDPUZDZURPP-UHFFFAOYSA-N
• IUPAC Name: trimethyl(trifluoromethyl)silane
• PubChem CID: 552549
• Percent Purity: 98%
• Sensitivity: Moisture sensitive
• Chemical Name or Material: (Trifluoromethyl)trimethylsilane

• CAS: 81290-20-2
• Linear Formula: (CH₃)₃SiCF₃
• UN Number: UN1993
• Flash Point: −10°C (14°F)
• Solubility Information: Soluble in alcohol,THF,ether,dichloromethane,aromatic and aliphatic hydrocarbons. Soluble in water(with white smokes).
• SMILES: CC(C)(C)[SiH2]C(F)(F)F
• Molecular Weight (g/mol): 156.22
• Formula Weight: 142.2
• Refractive Index: 1.3305
• Density: 0.962

Safety and Handling

GHS H Statement
H225-H315-H319-H335
Highly flammable liquid and vapour.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P332+P313-P363-P370+P378q-P501c

H225-H315-H319-H335

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Recommended Storage : Ambient temperatures

RUO – Research Use Only