(Trimethylsilyl)methyllithium, 0.7M (10 wt%) solution in hexanes, AcroSeal™, Thermo Scientific Chemicals

Product Code	Brand	Quantity
10366654	Thermo Scientific Acros 377451000	100 mL
10183064	Thermo Scientific Acros 377458000	800 mL

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Alkylation reagent

Specifications

• Chemical Name or Material: (Trimethylsilyl)methyllithium
• CAS: 1822-00-0, 92112-69-1, 92112-69-1
• CAS Max %: 14.0, 93.0
• Density: 0.6500g/mL
• Flash Point: −40°C
• Linear Formula: LiCH₂Si(CH₃)₃
• Specific Gravity: 0.65
• InChI Key: KVWLUDFGXDFFON-UHFFFAOYSA-N
• IUPAC Name: lithium;methanidyl(trimethyl)silane
• PubChem CID: 3482579
• Percent Purity: 7 to 14 wt%

• Name Note: 0.8M (12 wt%) solution in hexanes
• CAS Min %: 7.0, 86.0
• Color: Brown-Yellow to Colorless
• Boiling Point: 65.0°C to 70.0°C
• Molecular Formula: C₄H₁₁LiSi
• MDL Number: MFCD00010747
• Synonym: trimethylsilyl methyllithium, trimethylsilyl methyl lithium, lich2sime3, pubchem18144, tms-ch2li, lithiomethyltrimethylsilane, acmc-1bvf0, trimethylsilylmethyl lithium
• SMILES: [Li+].C[Si](C)(C)[CH2-]
• Molecular Weight (g/mol): 94.16
• Formula Weight: 94.16
• Physical Form: Solution

Safety and Handling

GHS H Statement
Highly flammable liquid and vapor.
May be fatal if swallowed and enters airways.
Causes severe skin burns and eye damage.
May cause drowsiness or dizziness.
Suspected of damaging fertility.
May cause d

GHS P Statement
Wear eye protection/face protection.
IF SWALLOWED: rinse mouth.
Do NOT induce vomiting.
IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses,if present and easy to do.
Continue rinsi

GHS Signal Word: Danger

Product Identifier

• (Trimethylsilyl)methyllithium, 0.7M (10wt%) solution in hexanes

Signal Word

• Danger

Hazard Category

• LONG-TERM AQUATIC HAZARD Chronic 2
• Flammable liquid Category 2
• Aspiration toxicity Category 1
• Skin corrosion/irritation Category 1 B
• Reproductive toxicity Category 2
• Specific target organ toxicity Category 3
• Specific target organ toxicity after repeated exposure Category 2
• Flammable liquid Category 2

Hazard Statement

• H225-Highly flammable liquid and vapour.
• H304-May be fatal if swallowed and enters airways.
• H314-Causes severe skin burns and eye damage.
• H336-May cause drowsiness or dizziness.
• H361f-Suspected of damaging fertility.
• H373-May cause damage to organs.
• H411-Toxic to aquatic life with long lasting effects.
• EUH014-Reacts violently with water.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.
• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P402+P404-Store in a dry place. Store in a closed container.

RUO – Research Use Only