Tocris Bioscience™ UNC 0642

Potent and selective G9a and GLP inhibitor

Brand:  Tocris Bioscience™ 5132/10

Product Code. 18712449

Description

UNC 0642 is a potent and selective G9a and GLP histone lysine methyltransferase inhibitor (IC50 < 2.5 nM) that exhibits >2,000-fold selectivity for G9a and GLP over PRC2-EZH2 and >20,000-fold selectivity over other methyltransferases. UNC 0642 reduces H3K9 dimethylation levels in MDA-MB-231 cells (IC50 = 110 nM), and displays modest brain penetration in vivo.

Specifications

• Purity: >99%
• Quantity: 10 mg
• Molecular Weight (g/mol): 546.7

• Content And Storage: -20°C
• Product Type: UNC 0642
• Inhibitors: UNC 0642

For Research Use Only