Thermo Scientific Chemicals uPA Inhibitor II, UK122

Product Code	Brand	Quantity
15496619	Thermo Scientific Chemicals J64874.MB	25 mg
15486619	Thermo Scientific Chemicals J64874.#0	5 mg

Description

A cell-permeable oxazolidinone-carboxamidine compound that acts as a potent, selective, and active-site targeting inhibitor of urokinase-type plasminogen activatoruPA Inhibitor II, UK122 acts as a potent, selective and active-site targeting urokinase-type plasminogen activator (uPA) inhibitor. However, its activity against trypsin, thrombin, tPA, and plasmin is greatly reduced. It is also effectively inhibits the migration (80% inhibition) and invasion (68% inhibition) of uPA-expressing CFPAC-1 pancreatic cells, without affecting its proliferation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• A cell-permeable oxazolidinone-carboxamidine compound that acts as a potent, selective, and active-site targeting inhibitor of urokinase-type plasminogen activator

Specifications

• Description: Yellow
• For Use With (Application): A cell-permeable oxazolidinone-carboxamidine compound that acts as a potent, selective, and active-site targeting inhibitor of urokinase-type plasminogen activator
• Formula Weight: 405.30g/mol
• Product Type: Signal Transduction Reagent

• Content And Storage: 2°C to 8°C
• Molecular Formula: C₁₇H₁₃N₃O₂·CF₃CO₂H
• Sensitivity: Light Sensitive
• Form: Solid

Safety and Handling

Recommended Storage : Keep cold

RUO – Research Use Only