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Tocris Bioscience™ XL 184

Potent VEGFR inhibitor; also inhibits other RTKs

Brand: Tocris Bioscience™ 5422/50

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Product Code. 18734909

£781.00 / 50mg

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Description

XL 184 is a potent VEGFR inhibitor (IC50 = 0.035 nM); also inhibits c-Met, KIT, RET, FLT4, AXL, FLT3, FLT1 and Tie2 (IC50 values are 1.3, 4.6, 5.2, 6, 7, 11.3, 12 and 14.3 nM, respectively). Induces intratumoral hypoxia and apoptosis. Reduces tumor invasion and metastasis in vivo. Antiangiogenic.

Specifications

Purity	>98%
Quantity	50 mg
Molecular Weight (g/mol)	501.51

Gene Alias	Cabozantinib, BMS 907351
Product Type	XL 184
Inhibitors	XL 184

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Tocris Bioscience™ XL 184

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