4-Aminobutyric acid, 99+%, Thermo Scientific Chemicals

Product Code	Brand	Quantity	Packaging
10775931	Thermo Scientific Acros 103280250	25 g	Plastic Bottle
10244030	Thermo Scientific Acros 103281000	100 g	Plastic Bottle
10518470	Thermo Scientific Acros 103285000	500 g	Plastic Bottle
15129153	Thermo Scientific Acros 103280025	2.5 kg	Plastic Bottle

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• 4-Aminobutyric acid is a γ-amino acid and monocarboxylic acid derived from butyric acid

• It is an amino acid that shows inhibitory activities against neurotransmitters, including GABA, and acts by binding GABA-A receptor and inhibiting the activity of signal-receiving neurons

• This compound, converted from neurotransmitter glutamate, is essential to regulate neuronal excitability

• It binds to GABA-A and GABA-B receptors, causing ion channel opening, hyperpolarization, and eventually inhibition of neurotransmission

Applications

• 4-Aminobutyric acid has been used in the preparation of GABA–BSA (bovine serum albumin)–GA (glutaraldehyde) conjugate, which is used as a control for immunohistochemical experiments

• It is used, in vivo, to detect GABA neurotransmitter by magnetic resonance spectroscopy

• This compound increases the production of short-chain fatty acids and decreases pH values in mouse colon

• Some in vivo experiments, using rats, mice, and pigs, demonstrated that 4-Aminobutyric acid can modulate intestinal fluid secretion, blood flow and ulceration

Chemical Identifiers

• CAS: 56-12-2
• Molecular Weight (g/mol): 103.12
• InChI Key: BTCSSZJGUNDROE-UHFFFAOYSA-N
• PubChem CID: 119
• IUPAC Name: 4-aminobutanoic acid

• Molecular Formula: C₄H₉NO₂
• MDL Number: MFCD00008226
• Synonym: 4-aminobutyric acid, gaba, gamma-aminobutyric acid, piperidic acid, piperidinic acid, aminalon, gaballon, gammalon, mielogen, butanoic acid, 4-amino
• ChEBI: CHEBI:16865
• SMILES: C(CC(=O)O)CN

Specifications

• Melting Point: 197°C to 204°C
• CAS Min %: 99.0
• Color: White
• Assay Percent Range: 99+%
• Molecular Formula: C₄H₉NO₂
• MDL Number: MFCD00008226
• Merck Index: 15,425
• Synonym: 4-aminobutyric acid, gaba, gamma-aminobutyric acid, piperidic acid, piperidinic acid, aminalon, gaballon, gammalon, mielogen, butanoic acid, 4-amino
• InChI Key: BTCSSZJGUNDROE-UHFFFAOYSA-N
• IUPAC Name: 4-aminobutanoic acid
• PubChem CID: 119
• Formula Weight: 103.12
• Physical Form: Crystalline Powder

• CAS: 56-12-2
• CAS Max %: 100.0
• Infrared Spectrum: Authentic
• Loss on Drying: 0.5% max.
• Linear Formula: H₂N(CH₂)₃CO₂H
• Beilstein: 04,413
• Transmittance: 95% min. (c=10, 2N HCl, 430nm) 1cm cell
• Solubility Information: Solubility in water: very soluble. Other solubilities: slightly soluble in common solvents
• SMILES: C(CC(=O)O)CN
• Molecular Weight (g/mol): 103.12
• ChEBI: CHEBI:16865
• Percent Purity: ≥99%
• Chemical Name or Material: 4-Aminobutyric acid, 99+%

Safety and Handling

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missing translation for 'tsca' : TSCA

Product Identifier

• 4-Aminobutyric acid

RUO – Research Use Only