Tocris Bioscience™ B I09

IRE1 endonuclease inhibitor; cell permeable

Brand:  Tocris Bioscience™ 6009/50

Product Code. 18780498

Description

B I09 is an IRE-1 RNase inhibitor (IC50 = 1.23 μM). Inhibits IRE-1/XBP1 pathway. Cell permeable. Inhibits growth of human chronic lymphocytic leukemia (CLL) cells in vitro and promotes CLL regression in a mouse model.

Specifications

• Color: Beige
• CAS: 1607803-67-7
• Formula Weight: 303.31g/mol
• Content And Storage: Store at -20°C
• Quantity: 50 mg

• Product Type: Inhibitor
• Molecular Formula: C₁₆H₁₇NO₅
• Solubility: Soluble to 50mM in DMSO
• For Use With (Application): Inhibits Rnase

For Research Use Only