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Invitrogen™ CellSensor™ AP-1-bla ME-180 Cell Line

CellSensor™ AP-1-bla ME-180 Cell Line

Brand:  Invitrogen™ K1661

Product Code. 10648723

  • £7810.00 / Each
Estimated Shipment: 04-02-2025
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Description

Description

The CellSensor™ AP-1-bla ME-180 Cell Line contains a beta-lactamase reporter gene under control of the AP-1 response element stably integrated into ME-180 cells. The cell line was created through FACS sorting of cells responsive to stimulation of the AP-1 pathway with Epidermal Growth Factor (EGF). This cell line was validated for DMSO tolerance, stimulant incubation time, substrate loading conditions, Z' and EC50 concentration of Epidermal Growth Factor. The AP-1-bla ME-180 Cell Line responds to agonist treatment as expected from the literature and can be adapted for high-throughput screening for agonists or antagonists of the AP-1 pathway with compound libraries. Candidate drugs can also be tested for dose response against this cell line. Academic and non-profit customers, please inquire for special pricing.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Cell-based beta lactamase reporter gene
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
1 vial
Cell Line
CellSensor™
Dividing Cells
CellSensor™
EGFR, ERK1/2, p38, MEK, MAPK pathway, c-MET, JNK, RON, RAF
ME-180
Signaling Pathway
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For Research Use Only. Not for use in diagnostic procedures.