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Clozapine N-oxide, Tocris Bioscience™ Product Code.: 30001356
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Clozapine N-oxide, Tocris Bioscience™

Product Code. 30001356
50 mg
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Quantity:
10 mg
50 mg
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Product Code. 30001356

Brand: Tocris Bioscience 4936/50

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This item is not returnable. View return policy

Description

Activator of muscarinic DREADDs

Metabolite of clozapine (Cat. No. 0444). Activates human muscarinic designer receptors (DREADDs) in vitro. Silences hippocampal neurons expressing hM4 DREADDs in vitro. Activates Gs-linked DREADDS- AgRP in mice via intracerebroventricular (i.c.v) injection. Shown to be a P-glycoprotein (P-gp) efflux pump substrate. Other potent and selective hM3Dq DREADD agonists available: DREADD agonist 21 and Perlapine .

Water soluble salt also available.

This product contains 1 molar equivalent of ethanol.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 34233-69-7
Molecular Formula C18H19ClN4O
Molecular Weight (g/mol) 342.827
InChI Key WYRDWWAASBTJLM-UHFFFAOYSA-N
Synonym clozapine n-oxide, clozapine-n-oxide, unii-mza8bk588j, chembl1688, mza8bk588j, n-oxyclozapine, clozapine n-oxide cno, oguczbiqsyywef-uhfffaoysa-nShow MoreShow Less
PubChem CID 2819
IUPAC Name 3-chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-5H-benzo[b][1,4]benzodiazepine
SMILES C[N+]1(CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl)[O-]

Specifications

Assay Percent Range >98%
Quantity 50 mg
Formula Weight 342.82
Percent Purity >99%
Chemical Name or Material Clozapine N-oxide

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