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Cycloheximide, Tocris Bioscience™

Product Code. 30001156
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Quantity:
100 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Inhibitor of protein synthesis

Selective inhibitor of eukaryotic (over prokaryotic) protein synthesis, blocking tRNA binding and release from ribosomes. Induces apoptosis in a variety of transformed and normal cell lines, including T cells. Competitively inhibits the PPIase hFKBP12 (Ki = 3.4 μM). Also inhibits ferroptosis. Antifungal antibiotic. Exhibits anti-MERS-CoV activity in Vero cells in vitro (IC50 = 0.16 μM).

Specifications

CAS 66-81-9
Molecular Formula C15H23NO4
MDL Number MFCD00082346
Quantity 100 mg
Synonym cycloheximide, actidione, cycloheximide, naramycin a, kaken, actidion, actidone, hizarocin, naramycin, neocycloheximide
InChI Key YPHMISFOHDHNIV-QTEFRXOUNA-N
SMILES [H][C@]1(C[C@@H](C)C[C@H](C)C1=O)[C@H](O)CC1CC(=O)NC(=O)C1
IUPAC Name 4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione
Molecular Weight (g/mol) 281.35
PubChem CID 6197
ChEBI CHEBI:27641
Formula Weight 281.35
Percent Purity >97%
Chemical Name or Material Cycloheximide
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