Decitabine, MedChemExpress

MedChemExpress Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity.

Brand:  Medchem Express HY-A0004

Product Code. 16487976

Description

Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity.

Specifications

• Chemical Name or Material: Decitabine
• Color: White
• Molecular Formula: C₈H₁₂N₄O₄
• Synonym: 5-Aza-2'-deoxycytidine 5-AZA-CdR NSC 127716
• SMILES: O=C1N=C(N)N=CN1[C@H](O[C@@H]2CO)C[C@@H]2O
• Formula Weight: 228.21
• Grade: Research
• For Use With (Application): Cancer-programmed cell death

• CAS: 2353-33-5
• Purity Grade Notes: Research
• Quantity: 100 mg
• Solubility Information: DMSO : ≥ 50 mg/mL (219.10 mM) ∣H2O : 20 mg/mL (87.64 mM; Need ultrasonic)
• Molecular Weight (g/mol): 228.21
• Percent Purity: 95.0%
• Physical Form: Solid

Research purposes only