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FGIN-1-27, Tocris Bioscience™
Potent, specific ligand for mitochondrial DBI receptor
£97.39 - £312.08
Chemical Identifiers
CAS | 142720-24-9 |
---|---|
Molecular Formula | C28H37FN2O |
Molecular Weight (g/mol) | 436.615 |
InChI Key | VUWXAQFLTSBUDB-UHFFFAOYSA-N |
Synonym | fgin-1-27, fgin 1 27, n,n-dihexyl-2-4-fluorophenyl indole-3-acetamide, fgin 1-27, n,n-di-n-hexyl-2-4-fluorophenyl indole-3-acetamide, chembl63154, 1h-indole-3-acetamide, 2-4-fluorophenyl-n,n-dihexyl, 2-2-4-fluorophenyl-1h-indol-3-yl-n,n-dihexylacetamide, tocris-0658 |
PubChem CID | 132496 |
IUPAC Name | 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide |
SMILES | CCCCCCN(CCCCCC)C(=O)CC1=C(NC2=CC=CC=C21)C3=CC=C(C=C3)F |
Description
Binds specifically and with high affinity to the peptide DBI receptor (benzodiazepine receptor) on mitochondrial membranes, inducing production of neurosteroids, which modulate GABA receptors (EC50 = 3 nM for increase in production of pregnenolone in glial cells). Thus it reduces anxiety without causing sedation.Chemical Identifiers
142720-24-9 | |
436.615 | |
fgin-1-27, fgin 1 27, n,n-dihexyl-2-4-fluorophenyl indole-3-acetamide, fgin 1-27, n,n-di-n-hexyl-2-4-fluorophenyl indole-3-acetamide, chembl63154, 1h-indole-3-acetamide, 2-4-fluorophenyl-n,n-dihexyl, 2-2-4-fluorophenyl-1h-indol-3-yl-n,n-dihexylacetamide, tocris-0658 | |
2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide |
C28H37FN2O | |
VUWXAQFLTSBUDB-UHFFFAOYSA-N | |
132496 | |
CCCCCCN(CCCCCC)C(=O)CC1=C(NC2=CC=CC=C21)C3=CC=C(C=C3)F |
Specifications
142720-24-9 | |
fgin-1-27, fgin 1 27, n,n-dihexyl-2-4-fluorophenyl indole-3-acetamide, fgin 1-27, n,n-di-n-hexyl-2-4-fluorophenyl indole-3-acetamide, chembl63154, 1h-indole-3-acetamide, 2-4-fluorophenyl-n,n-dihexyl, 2-2-4-fluorophenyl-1h-indol-3-yl-n,n-dihexylacetamide, tocris-0658 | |
CCCCCCN(CCCCCC)C(=O)CC1=C(NC2=CC=CC=C21)C3=CC=C(C=C3)F | |
436.615 | |
436.61 | |
FGIN-1-27 |
C28H37FN2O | |
VUWXAQFLTSBUDB-UHFFFAOYSA-N | |
2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide | |
132496 | |
>98% |
Safety and Handling
Recommended Storage : Store at Room Temperature