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Description
Selective lysophosphatidic acid 2 (LPA2) receptor non-lipid agonist (EC50 = 3.3 μM). Does not activate other LPA GPCRs at concentrations up to 10 μM. Antiapoptotic; inhibits activation of caspases 3, 7, 8 and 9, Bax translocation and PARP-1 cleavage. Activates ERK1/2 survival pathway.

Specifications
Specifications
Quantity | 50 mg |
Formula Weight | 391.44 |
Percent Purity | >98% |
Chemical Name or Material | GRI 977143 |
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GRI 977143, Tocris Bioscience™ >
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