Cytiva HiScreen™ MabSelect™, Xtra™, SuRe™, SuRe LX™ Prepacked Columns

Designed for method optimization and parameter screening for capture of monoclonal antibodies. Cytiva HiScreen™ MabSelect™, Xtra™, SuRe™, SuRe LX™ Prepacked Columns come ready-to-use for convenience.

Product Code	Brand	Ligand	Product Type
10811291	Cytiva 28-9269-73	Recombinant Protein A (E.coli)	HiScreen MabSelect Prepacked Column
10049569	Cytiva 28-9269-77	Alkali-stabilized Protein A-derived (E. coli)	HiScreen MabSelect SuRe Prepacked Column
11603084	Cytiva 17-5474-15	Alkali-stabilized Protein A-derived (E. coli)	HiScreen MabSelect SuRe LX Prepacked Column
10039569	Cytiva 28-9269-76	Recombinant Protein A (E.coli)	HiScreen MabSelect Xtra Prepacked Column

Description

• Ready-to-use columns for convenient process development
• Rigid, highly cross-linked agarose matrix
• Bed height of 10cm is designed to allow method optimization and parameter screening
• Easily connected in series to achieve 20cm bed height
• Small bed volume (4.7mL) gives fast result and minimal sample/buffer consumption
• Reproducible results, scalable to BioProcess columns packed with the same chromatography media using the same linear fluid velocity

MabSelect

• For capture of MAbs from large sample volumes
• Prepacked with protein A-derived media
• Compatible with high flow rates and high pressure when scaling up

MabSelect Xtra

• Increased binding capacity enables purification of MAbs from high-level expression feedstock
• Also optimized for Fc-fusion proteins
• Very low, unspecific binding due to high ligand selectivity and matrix hydrophilicity
• Prepacked with protein A-derived media

MabSelect SuRe (Superior Resistance) and MabSelect SuRe (Superior Resistance) LX

• With novel, alkali-tolerant recombinant protein A ligand that provides greater stability and allows use of 0.1 to 0.5M sodium hydroxide for cleaning-in-place (CIP)
• Enhanced protease resistance resulting in lower ligand leakage
• High dynamic binding capacity

Specifications

• Buffer: 8M Urea, 6M Guanidine Hydrochloride, 2% Benzyl Alcohol or 20% Ethanol
• Kit Size: 1 x 4.7mL
• Diameter (English) Inner: 0.3 in.
• Height (English) Bed: 3.93 in.
• Material: Polypropylene
• Format: Column

• Includes: Stoppers at the inlet and outlet
• Bed Support: Filter
• Diameter (Metric) Inner: 0.77cm
• Ligand Coupling Method: Epoxy Activation
• Storage Requirements: 2° to 8°C

Safety and Handling

Product Identifier

• HiScreen MabSelect

Signal Word

• Warning

Hazard Category

• Flammable liquid Category 3

Hazard Statement

• H226-Flammable liquid and vapour.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information

• MIXTURE LIST-Contains : ethanol