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Eurofins DiscoverX IKKε Protein, Active
Active, N-terminal FLAG and GST-tagged, recombinant, human IKKε, full length, for use in Kinase Assays.
£448.44 - £3422.71
Specifications
| Formulation | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 150 mM NaCl, 10 mM β-glycerophosphate, 1 mM sodium orthovanadate, 1 mM NaF, 28% v/v glycerol, 0.03% Brij-35, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
|---|---|
| Molecular Weight (g/mol) | 109 kDa |
| Species | Human |
| Recombinant | Recombinant |
| Protein Tag | N-terminal FLAG and N-terminal GST |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17300804
|
Eurofins DiscoverX
14-926 |
10 μg |
£448.44
10µg |
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|
17310804
|
Eurofins DiscoverX
14-926M |
250 μg |
£3422.71
250µg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
IKBKE is a noncanonical I-kappa-B kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. May play a special role in the immune response. Protects cells against DNA damage-induced cell death.
GenBank NM_014002
Specifications
| mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 150 mM NaCl, 10 mM β-glycerophosphate, 1 mM sodium orthovanadate, 1 mM NaF, 28% v/v glycerol, 0.03% Brij-35, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. | |
| Human | |
| N-terminal FLAG and N-terminal GST | |
| Full-length | |
| IKKε, active |
| 109 kDa | |
| Recombinant | |
| Recombinant enzyme expressed in Sf21 insect cells | |
| ≥65% |