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JZP 361, >99%, Tocris Bioscience™
Potent and selective reversible MAGL inhibitor
£90.00 - £323.00
Specifications
| Chemical Name or Material | [4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl](1H-1,2,4- |
|---|---|
| CAS | 1680193-80-9 |
| Purity Grade Notes | >99% |
| Linear Formula | C22H20ClN5O |
| Solubility Information | Soluble to 100mM in DMSO and to 20mM in ethanol |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
30000795
|
Tocris Bioscience
5851/10 |
10 mg |
£90.00
10mg |
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|
30000842
|
Tocris Bioscience
5851/50 |
50 mg |
£323.00
50mg |
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Description
Potent and selective reversible MAGL inhibitor (IC50 = 46 nM). Exhibits 35-fold and 150-fold higher selectivity over human FAAH and ABHD6, respectively (IC50 values are 1.79 and 7.24 μM, respectively). Displays affinity for H1 receptors (pA2 = 6.81). Exhibits no activity at cannabinoid receptors at 10 μM.Specifications
| [4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl](1H-1,2,4- | |
| >99% | |
| Soluble to 100mM in DMSO and to 20mM in ethanol |
| 1680193-80-9 | |
| C22H20ClN5O | |
| 405.88 |
Safety and Handling
Recommended Storage : Store at 4deg;C
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