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  8. 30000842

JZP 361, >99%, Tocris Bioscience™

Potent and selective reversible MAGL inhibitor

Brand:  Tocris Bioscience 5851/50

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Product Code. 30000842

  • £323.00 / 50mg

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Description

Description

Potent and selective reversible MAGL inhibitor (IC50 = 46 nM). Exhibits 35-fold and 150-fold higher selectivity over human FAAH and ABHD6, respectively (IC50 values are 1.79 and 7.24 μM, respectively). Displays affinity for H1 receptors (pA2 = 6.81). Exhibits no activity at cannabinoid receptors at 10 μM.
Specifications

Specifications

[4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl](1H-1,2,4-
>99%
50 mg
405.88
1680193-80-9
C22H20ClN5O
Soluble to 100mM in DMSO and to 20mM in ethanol
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