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Tocris Bioscience™ PD 98059

MEK inhibitor

£94.00 - £615.00

Specifications

Purity 98%
Molecular Formula 2-(2-Amino-3-methoxyphenyl)-4 H-1-benzopyran-4-one
CAS 167869-21-8
Content And Storage Room Temperature
Product Type PD 98059
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18073852
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Tocris Bioscience™
1213/1
1 mg
£94.00
1mg
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18033882
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Tocris Bioscience™
1213/50
50 mg
£615.00
50mg
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18708126
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Tocris Bioscience™
1213/10
10 mg
£165.00
10mg
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Description

Description

Inhibitor of mitogen-activated protein kinase kinase (MKK/ MEK). Acts by binding to the inactivated form of MEK, thereby preventing its phosphorylation by cRAF or MEK kinase (IC50 = 2-7 μM). Inhibits cell growth and proliferation in acute myelogenous leukemia (AML) cell lines; causes G1 arrest by blocking p53-dependent p21 induction. Enhances embryonic stem cell self-renewal.
Specifications

Specifications

98%
167869-21-8
PD 98059
PD 98059
2-(2-Amino-3-methoxyphenyl)-4 H-1-benzopyran-4-one
Room Temperature
M.W. (Observed): 267.28
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